Project 3

Development of validated and predictive Quantitative Structure-Toxicity Relationship models that employ both chemical and biological descriptors of molecular structures and take into account genetic diversity between individuals

Personnel

Alexander Tropsha, PhD

Principal Investigator
K.H. Lee Distinguished Professor and Chair
Division of Medicinal Chemistry and Natural Products
Eshelman School of Pharmacy
Beard Hall Rm. 327A
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-7360
alex_tropsha@unc.edu

Hao Zhu, PhD

Investigator
Research Assistant Professor
Division of Medicinal Chemistry and Natural Products
Eshelman School of Pharmacy
Beard Hall Rm. 327A
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-7360
haozhu@email.unc.edu

Aleks Sedykh, PhD

Postdoctoral Fellow
Division of Medicinal Chemistry and Natural Products
Eshelman School of Pharmacy
Beard Hall Rm. 327A
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-7360
sedykh@email.unc.edu

Liying Zhang

Graduate Research Assistant
Division of Medicinal Chemistry and Natural Products
Eshelman School of Pharmacy
Beard Hall Rm. 327A
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-7360
zhangly@email.unc.edu